Frequently Asked Questions

What is Breezy Blue^®?

Breezy Blue^® (Breezy) is a touchless whole-room disinfection system that applies aerosolized hydrogen peroxide to disinfect hospital rooms, equipment and facilities. Breezy Blue® provides automated, push-button room disinfection using compatible EPA-registered hydrogen peroxide disinfectants, with efficacy against label-listed microorganisms supported by laboratory testing. 

How does Breezy work?

Breezy emits a dry fog (micron-sized particles) of aerosolized hydrogen peroxide disinfectant that fills a room and uniformly covers all surfaces—including hard-to-reach areas, equipment and fabrics—without leaving residue or moisture. For most rooms, the total treatment time is less than 15 minutes and requires near-zero labor. This includes the fogging cycle, contact time, and ventilation, making it an efficient final step in the cleaning process.

Within which areas of a hospital can Breezy be used?

Breezy is suitable for:

Can Breezy be used during clinical downtime or within a short turnover window?

Yes. Most spaces are ready for reentry within 15 minutes (including the fogging cycle, contact time, and hydrogen peroxide evaporation). Fogging time and total treatment time can be calculated for your specific disinfection parameters using our Fogging Time Calculator.

Can Breezy be used in occupied areas?

No. Breezy should not be used in actively occupied spaces. It is designed for use between patients, during shift changes, or when spaces are unoccupied.

Is Breezy safe to use around electronics and medical equipment?

Yes. The dry fog is non-corrosive, leaves no residue, and is safe around monitors, electronics, and medical equipment.

What PPE is required during fogging?

No PPE is required while fogging if you remain outside the room. If reentering during the 15-minute treatment time, wear eye protection and a mask.

Why is Breezy better than disinfecting by hand or with UV systems?

Breezy Blue® delivers superior efficacy, consistency, and efficiency compared to manual disinfection or UV light systems:

Why it matters:

Manual cleaning is vulnerable to human error and rarely reaches >90% coverage. UV systems are limited to line-of-sight and require multiple cycles to compensate for shadowed zones. In contrast, Breezy’s aerosolized hydrogen peroxide dry fog uniformly fills the space, reaching difficult areas, while Breezy Cloud™ validates performance with automated logs. Peer-reviewed studies have demonstrated that aerosolized hydrogen peroxide disinfection can reduce environmental contamination by healthcare-associated pathogens, including C. difficile, under studied conditions.

What pathogens does Breezy Blue® disinfect against?

Breezy Blue® uses an EPA-registered hydrogen peroxide disinfectant (EPA Reg. No. 84526-1) with demonstrated efficacy against a range of bacteria, viruses, and fungi, including MRSA, Pseudomonas aeruginosa, E. coli, norovirus, and influenza viruses. See our Germicidal Efficacy Summary for the complete list of EPA-registered organisms and applicable treatment conditions.

Is Breezy effective against COVID-19?

Yes. Breezy Blue® uses an EPA-registered hydrogen peroxide disinfectant included on EPA List N for use against SARS-CoV-2, the virus that causes COVID-19. Peer-reviewed research also supports the effectiveness of aerosolized hydrogen peroxide against SARS-CoV-2 on surfaces under studied conditions (PLOS One 2022).

Is Breezy effective against measles?

Hydrogen peroxide disinfectants have demonstrated efficacy against enveloped viruses, the category that includes measles. Breezy Blue® uses an EPA-registered hydrogen peroxide disinfectant with efficacy claims against several enveloped viruses, providing a strong scientific basis for its potential effectiveness against measles.

Is Breezy effective against tuberculosis (TB)?

Hydrogen peroxide disinfection technologies have demonstrated effectiveness against Mycobacterium tuberculosis and related mycobacteria. Peer-reviewed studies support the use of hydrogen peroxide vapor for inactivating these organisms under defined treatment conditions (J Clin Microbiol 2007, Lett Appl Microbiol 2005).

Is Breezy effective against Clostridium difficile?

Yes, evidence strongly supports the effectiveness of Breezy Blue® against Clostridium difficile (C. diff) spores. A 10-year hospital study showed that aerosolized hydrogen peroxide systems reduced C. diff infection rates by more than 40%, with sustained additional improvements over time (AJIC 2022). Breezy Med has validated its Standard and Deep disinfection protocols through extensive internal testing with Bacillus atrophaeus biological indicators (BIs), using nominal 4-log and 6-log spore-reduction targets, respectively. These resistant bacterial spores provide a rigorous biological challenge for evaluating disinfection performance. Combined with published clinical research demonstrating reductions in C. difficile infections following aerosolized hydrogen peroxide disinfection, this evidence supports Breezy Blue® as a valuable supplemental tool in hospital infection prevention programs.

Is Breezy effective against Candida auris?

Yes. Laboratory testing of Breezy Blue® using aerosolized hydrogen peroxide demonstrated approximately 4-log reductions (99.98–99.99%) of Candida auris across multiple locations and surface orientations in an environmental test chamber. These findings support Breezy Blue® as a supplemental environmental disinfection option for hospitals managing C. auris contamination.

What clinical studies have been done?

Breezy Med has completed multiple clinical and pre-clinical studies evaluating the efficacy, workflow impact, and safety of automated aerosolized hydrogen peroxide disinfection.

A peer-reviewed article in the Journal of Visualized Experiments (JoVE 2026) details Breezy's automated aerosolized hydrogen peroxide hospital room disinfection protocols. The study, developed through multi-disciplinary collaboration among hospital infection prevention leaders and clinical colleagues, evaluates automated aerosolized hydrogen peroxide as part of terminal cleaning in environments affected by carbapenem-resistant organisms (CROs) and other multidrug-resistant organisms (MDROs). 

Additional published research supports the use of aerosolized hydrogen peroxide in healthcare environments. A 10-year hospital study showed that aerosolized hydrogen peroxide systems reduced C. difficile infection rates by more than 40% (AJIC 2022).  Other studies have demonstrated >90% reductions in bacterial burden on noncritical medical equipment (AJIC 2020) and significant reductions in gram-positive bacteria in hospital environments  (AJIC 2025).

Breezy Med has also presented clinical findings at leading infection prevention conferences, including APIC and AHE. For example, a study at the Rehabilitation Hospital of Southern New Mexico demonstrated reduced transmission of carbapenem-resistant organisms (CROs) using automated aerosolized hydrogen peroxide disinfection as part of a comprehensive process improvement program.

To explore our current and ongoing clinical studies—or to participate as a co-author with minimal additional workload—visit our Clinical Evidence & Research webpage. 

How is disinfection performance monitored and documented within my hospital?

During deployment, Breezy uses electrochemical sensors (Breezy Trace™) to measure hydrogen peroxide exposure and assess treatment conditions against protocols developed through Bacillus atrophaeus biological indicator (BI) testing. Breezy Trace™ can also provide ongoing exposure monitoring for quality assurance. Treatment and exposure data are recorded in Breezy Cloud™, enabling hospitals to review treatment records, monitor system usage, and access performance data through centralized dashboards.

Does Breezy leave residue, odors, or damage surfaces?

No. Breezy Blue® produces a fine aerosolized hydrogen peroxide fog designed to minimize surface moisture and residue. Hydrogen peroxide breaks down into water and oxygen, and Breezy-approved chemical solutions are selected for compatibility with intended applications.

Are Breezy-approved chemical solutions safe and environmentally responsible?

Breezy-approved chemical solutions are selected for safety, performance, and compatibility with intended applications. Our EPA-registered hydrogen peroxide disinfectant is classified as practically non-toxic (EPA Toxicity Category IV), is biodegradable, and contains no VOCs, bleach, or phenols.

Are airborne silver concentrations safe during Breezy disinfection?

Yes. Air monitoring conducted during Breezy Blue® fogging with our EPA-registered hydrogen peroxide disinfectant found airborne silver concentrations below the test method's detection limit (2.5 µg/sample) when following recommended treatment protocols. Testing was performed using a modified NIOSH 7030 method.

How is Breezy Blue^® operated?

Breezy Blue® is extremely simple to use and is operated with minimal labor and without chemical exposure. This video shows Breezy in use. In general, there are three modes of operation:

•    Scheduled autonomously (e.g. unattended overnight use).

It typically takes 15 minutes total to treat a room after positioning Breezy and starting the fogging with one of its push buttons. You do not have leave Breezy inside the room if you fog from the doorway and close the door after the fog dispenses. In this manner, you can treat multiple rooms back-to-back every few minutes.

What is the difference between Quick and Full fogging modes?

Full mode (Gen2 Smart Controllers only) is the recommended default for most applications. It dispenses fog at a reduced rate to improve whole-room coverage (including floor-to-ceiling and complex geometries), and reduces the risk of condensation. Full mode has undergone more extensive biological indicator (BI) validation testing. Users simply select room size and desired treatment, and dispensing time is set automatically.

Quick mode dispenses fog at a faster rate. Because Quick mode dispenses more rapidly, it may create minor floor condensation in larger spaces or during longer cycles. It is appropriate for:

•     Situations where Breezy is operated from the doorway and the room door is closed immediately after dispensing.

Note: Full mode protocols apply to Gen2 Smart Controllers only. Gen1 Smart Controllers only offer Quick fogging mode.

How long does it take to treat a room and how much chemical is used?

Breezy Blue offers Standard and Deep treatment protocols. These protocols are designed around nominal 4-log and 6-log Bacillus atrophaeus biological-indicator reduction targets established through internal testing. These targets are not guarantees of microbial reduction in every treatment environment. Actual outcomes depend on room configuration, environmental conditions, disinfectant exposure and other variables.

Fog dispensing time, treatment time and chemical usage depends on room size and selected treatment protocol. Each gallon provides approximately 15 minutes (900 seconds) of dispensing time. Specific parameters and examples for the two fogging modes are as follows.

Quick Mode

•     Fog dispensing time and total treatment time for Quick mode can be calculated using our Fogging Calculator. 

What is the maximum room size for Breezy Blue^® fogging?

Breezy Blue® can disinfect rooms up to about 1,000 square feet (10,000 cubic feet), with a maximum single dimension of ~40 feet. Larger spaces or high ceilings may require multiple units running simultaneously to achieve full, even coverage across the entire space.

What is the role of the Breezy Smart Controller?

The Breezy Smart Controller configures settings, schedules fogging, pushes updates, and tracks device usage. It connects via Bluetooth (no Wi-Fi needed) and logs activity to Breezy Cloud™.

What are the training and maintenance requirements?

Breezy requires minimal training. Environmental services staff are typically up and running the system in less than 30 minutes. Cleaning involves occasional filter checks and wiping the exterior. No routine maintenance is needed.

How long will Breezy Blue^® last in regular use?

Breezy Blue® has been designed and third-party lab validated for ruggedness, safety and electromagnetic compatibility. Service life validation tests were performed to ensure a minimum of 1,100 hours of fogging operation, which equals to 5 years of service at 36 minutes per day of fogging.

Should I remove the antimicrobial solution from Breezy Blue^® when the system is not in use?

No. Breezy Blue® has a sealed chemical reservoir, allowing Breezy-approved chemical solutions to remain in the system between uses. When stored under recommended conditions, the solution maintains the same shelf life as specified for its original container.

Will the fog set off smoke detectors?

When the Breezy foggers are used according to our instructions for use, the dry fog will not set off smoke detectors. Do not point the Breezy foggers directly at a smoke detector.

Are there any objects or materials that I should not fog around?

You can safely fog around most objects and materials including electronics, fabrics, papers, most metals, leathers, and wood surfaces. Avoid fogging people, pets, plants and unwrapped food. Avoid fogging around untreated soft metals like aluminum and brass, and avoid fogging any antiquities on which you would not allow water. Also, avoid fogging kitty litter, as many litters contain alkaline compounds that can react with hydrogen peroxide and cause unwanted chemical reactions and noxious odors. Contact Breezy Med if you have specific compatibility questions.

Can Breezy integrate with hospital automation platforms?

Yes. Breezy Cloud™ offers API access for integration with hospital automation and Real-Time Location System (RTLS) software platforms. Breezy is presently integrated within the BedWatch bed management platform.

What are my procurement options?

Hospitals can purchase a Base System or enter a 12-month subscription that includes all equipment, warranty, data platform, upgrades, support and training. Pricing details are available online.

Is Breezy cost-effective compared to UV systems?

Yes. Not only does Breezy offer more complete whole-room coverage and higher efficacy than UV systems, Breezy is about 10% the cost of a UV system. Here is a detailed comparison of Breezy vs. UV disinfection within a healthcare environment.

How does Breezy compare to other hydrogen peroxide systems?

Compared to many legacy hydrogen peroxide systems, Breezy offers faster workflows, easier routine use, and significantly lower cost of ownership while still delivering validated whole-room disinfection efficacy. Here is a detailed comparison of Breezy vs. legacy hydrogen peroxide room disinfection systems.

How do I calculate the cost and return on investment for my hospital?

We have an on-line calculator that allows you to enter your hospital data to calculate your total costs, expense savings, and ROI when you move to Breezy Blue® for your terminal cleaning.

How does Medicare reimbursement affect environmental disinfection costs for Critical Access Hospitals?

Critical Access Hospitals receive Medicare cost-based reimbursement for allowable expenses attributable to covered Medicare services. Environmental disinfection equipment subscriptions can contribute to this reimbursement through the hospital's cost-reporting process. Learn more about Critical Access Hospital reimbursement.

How do I evaluate Breezy for my hospital?

Contact Breezy Med at info@breezymed.com or use our contact form for evaluation programs, capital purchase guidance, or more information. We would be happy to schedule a demo for your infection prevention, EVS and nursing teams.