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Breezy aHP vs. Legacy H2O2

Breezy aHP vs. Legacy Hydrogen Peroxide Systems

High-level disinfection, built for real hospital workflows

Hydrogen peroxide (HP) systems are widely used because they work. When applied correctly, all HP technologies can achieve strong pathogen reduction. This efficacy is driven by the generation of hydroxyl radicals (·OH), which disrupt proteins, lipids, and cell membranes, leading to microbial inactivation.

Hydroxy radical oxidation cycle
When aerosolized, hydrogen peroxide (H₂O₂) generates reactive hydroxyl radicals (·OH) that oxidize and disrupt essential biomolecules, leading to rapid inactivation of pathogens and conversion into harmless byproducts (H₂O and O₂). 

Figure 1: Mechanism of Action of Aerosolized Hydrogen Peroxide (aHP) 

Breezy Blue®'s difference is operational: speed, simplicity, and consistency in real hospital use.

Breezy’s aerosolized hydrogen peroxide (aHP) is designed to deliver the same high-level disinfection with faster cycles, simpler workflows, and reliable whole-room coverage.

How Breezy aHP Works Differently

Breezy uses a high-output aerosol approach to rapidly fill a room with disinfecting droplets:
  • High concentration of droplets <10 microns for full-room distribution
  • High airflow + output delivers ~10x more droplets in the same time 
  • Higher droplet concentration provides effective surface deposition
Unlike vapor and slow-cycle systems, Breezy:
  • Reaches effective coverage quickly
  • Keeps droplets contained within a closed room
  • Avoids long dispersion times that drive complexity

Result: fast, even, repeatable disinfection.

Distinction Between aHP and AHP Terminology

The term AHP can refer to accelerated hydrogen peroxide (hydrogen peroxide with added chemicals such as surfactants or organic acids). These additives can introduce residue or material compatibility concerns and are generally unnecessary in aerosolized systems, where micron-scale droplets increase surface area and facilitate hydroxyl radical (·OH) generation.

Breezy uses aHP (aerosolized hydrogen peroxide)
  • Pure hydrogen peroxide formulation
  • No added accelerants associated with irritation or material incompatibility
  • Decomposes into water and oxygen, leaving no residues

Operational Implications

Compared to vapor and slow-cycle hydrogen peroxide systems, Breezy aHP enables more rapid room coverage, reduced reliance on room sealing, and shorter overall treatment cycles. These differences support more consistent implementation within routine hospital workflows, with lower variability and reduced downtime between uses.

Feature Breezy aHP
Vapor / Slow-Cycle aHP 
Total treatment Time 15 minutes Up to many hours
Room sealing Not typically required Often required
Humidity / Condensation Low due to short cycles Moderate-to-high during long treatments
Workflow Simple, repeatable More complex
Coverage Rapid, whole-room Slower, sealing-dependent
 

The Bottom Line

All hydrogen peroxide systems disinfect.
Breezy is designed to make it practical at scale in hospitals
  • Faster cycles
  • Simpler workflows
  • Reliable coverage
  • Clean chemistry

Scientific Background

Modeled Droplet Dispersion and Rapid Room Coverage

In computational fluid dynamics modeling of a standard hospital room, aerosolized hydrogen peroxide droplets achieved full-room surface coverage within 1 minute of dispersion. The simulation in Figure 1 demonstrates how Breezy’s high-output aerosol rapidly distributes throughout the space, supporting consistent, whole-room disinfection.

Breezy Blue Droplet Spraying 2

Figure 2: Computational fluid dynamics model of Breezy's droplet dispersion

Clinical Evidence and Research Network

Breezy is supported by a growing network of infection prevention leaders, clinicians, and healthcare institutions evaluating aerosolized hydrogen peroxide in real-world settings.

This work includes:
  • Peer-reviewed publications and clinical protocols
  • Hospital-based studies on MDRO transmission reduction
  • Preclinical testing across emerging pathogens, including Candida auris
  • Ongoing collaboration with infection prevention professionals across multiple care settings

Together, these efforts provide a foundation of clinical validation, practical implementation, and continuous improvement. Explore our Clinical Evidence and Research Network.

See the Science. See Breezy in Practice.